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Citalopram, sold under the brand name Celexa among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [7][9] It is used to treat major depressive disorder, obsessive-compulsive disorder, panic disorder, and social anxiety disorder. [7] Citalopram is used to treat depression. Citalopram is in a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs). It works by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance. CELEXA contains citalopram, a selective serotonin reuptake inhibitor (SSRI). Citalopram hydrobromide is a racemic bicyclic phthalane structure and is designated (±)-1- (3-dimethylaminopropyl)-1- (4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile hydrobromide with the following structural formula: Celexa is an antidepressant prescription medicine used to treat depression and major depressive disorder. Celexa may cause serious side effects. 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